Freaks, a 1932 film movie directed by Tod Browning (also famous for Dracula with Bela Lugosi), is available for your viewing horror/amazement/pleasure on Google video. Browning casted real people with deformities as the eponymous sideshow “freaks”, rather than using costumes and makeup. He intended to portray the classic moral of how beauty on the outside does not necessarily equate to beauty on the inside.
Reaction to this film was so intense that Browning had trouble finding work afterwards, and this in effect brought his career to an early close. The movie was banned in the UK for thirty years.