In-Potentia, from foreskin cells to 'biological brain'
It's been too long since i've blogged about a project supported by Symbiotica (although they did get their fair amount of mentions and praises in #A.I.L., the show i present on ResonanceFM.)
For the In-Potentia work, the artists grew cells that were taken from human foreskin cells purchased from an online catalogue. The cells were then re-programmed by genetic manipulation and bio-engineered to become a neural network.
This functioning "brain" is presented in a sculptural incubator containing custom-made automated feeding and waste retrieval system as well as an electrophysiological recording setup.
The work is more clearly explained in the video below:
In-Potentia exposes, in the most limpid and absurd way, how science is blurring what we are used to regard as clear-cut categories, such as where life begins and ends or what constitutes a person. Or in Guy Ben-Ary's words:
What is the potential for artists employing bio-technologies to address, and modify, boundaries surrounding understandings of life, death and person-hood? And what exactly does it mean culturally, artistically, ontologically, philosophically, politically and ethically to make a living biological brain from human foreskin cells?
The artists have kindly accepted to answer my questions:
In Potentia is without doubt a very powerful and thought-provoking work. What is the state of the scientific but also cultural debate around liminal forms of life? where could i read more about it (in a not too daunting, hi-tech language if possible)? do you have simple examples of these 'uncertain lives' at the border between human/non-human, coherent/hybrid, etc.?
Liminal lives can be "brain dead" or coma patients who are only being kept alive due to machinic intervention, or severely pre-term newborns kept alive with external life support systems, or embryos (both within or outside of a female host body) whose status as "pre-beings" disrupts our understanding of "life" as being conscious, independent and "useful". Liminal lives could also be humans with animal (or other human) organ transplants, genetically modified/manipulated (human and non-human) lives that challenge the ontological status of where and how "life" starts, or even non-humans that exhibit "human-like" characteristics of consciousness etc etc. A liminal life can therefore be found anywhere that our traditional western understandings of what it means to be human is challenged, altered or transgressed. If you were only going to read one thing on liminal lives, I would suggest Susan M Squire's 2004 seminal text: Liminal Lives - Imagining the Human at the Frontiers of Biomedicine.
I like the humour behind 'project dickhead' as you nicknamed it but i've been wondering if you're not worried that certain journalists (and bloggers) will jump on the opportunity to depict the project in a simplistic light? Your choice was quite bold because you could have avoided potential simplistic headlines by choosing to use other cells than the ones of foreskin?
Could you briefly explain me the audio-soundscape that exposes the electrical activity of neural signals or synaptic output? It is just the electrical activity from the neural network being amplified? Did you modify the sound in any way to make it more 'evocative' of what the activity of a brain might sound like?
Thanks Guy and Kirsten!